Long-Term Effects of COVID-19 Vaccines: Should You Be Worried?

Kim’s Convenience is a very wholesome and excellent show. I receive no remuneration for stating that. But it’s on Netflix and you should watch it because I said so.
  1. An effect of the vaccine that arises soon after its receipt and has long-term consequences on the vaccinee.
  2. An effect of the vaccine that arises years after the initial vaccination (I would prefer to call this a latent adverse event following immunization (LAEFI) but this is what many are calling a long-term effect so I’ll be consistent with their language).
A summary of how varicella infection works. In short, the virus enters the body and establishes an infection in the cell and undergoes latency- a quiescent from where the virus persists in the form of DNA called an episome. Then, if the immune system undergoes some kind of suppression, the virus can reactivate inside neurons, causing shingles, or meningitis, or encephalitis. Because the vaccine is attenuated, this is much less likely to happen from it than from infection, which it reliably protects against, but it is nontheless a nonzero risk. From: https://www.nature.com/articles/nrmicro3215
From Principles of Virology Volume 2 4th Edition Table 5.2 by Flint, Racaniello, Rall, Skalka, and Lehnquist
This is a WHO guidance regarding the monitoring of adverse events. From: https://www.who.int/biologicals/expert_committee/WHO_TRS_1004_web_Annex_9.pdf?ua=1&fbclid=IwAR1mD01SsAenS3lOEzJwyXwGjAbV2C9yV-FOTkpaNj-BvmvHfaMu_gx3gL0

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I write about vaccines here. You can find me on Twitter @enirenberg and at deplatformdisease.com (where I publish the same content without a paywall)

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Edward Nirenberg

Edward Nirenberg

I write about vaccines here. You can find me on Twitter @enirenberg and at deplatformdisease.com (where I publish the same content without a paywall)

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